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Am J Med. 2016 Oct;129(10):1037-43. doi: 10.1016/j.amjmed.2016.05.012. Epub 2016 Jun 4.

Fungal Endocarditis: Update on Diagnosis and Management.

Author information

1
Department of Medicine, University of Arizona, Tucson.
2
Division of Cardiovascular Disease, Department of Medicine, University of Arizona, Tucson.
3
Division of Infectious Disease, Department of Medicine, University of Arizona, Tucson. Electronic address: malmohajer@email.arizona.edu.

Abstract

Fungal endocarditis is an extremely debilitating disease associated with high morbidity and mortality. Candida spp. are the most common isolated organisms in fungal endocarditis. It is most prevalent in patients who are immunosuppressed and intravenous drug users. Most patients present with constitutional symptoms, which are indistinguishable from bacterial endocarditis, hence a high index of suspicion is required for pursuing diagnosis. Diagnosis of fungal endocarditis can be very challenging: most of the time, blood cultures are negative or take a long time to yield growth. Fungal endocarditis mandates an aggressive treatment strategy. A medical and surgical combined approach is the cornerstone of therapy.

KEYWORDS:

Aspergillus; Candida; Emboli; Endocarditis; Fungal

PMID:
27267285
DOI:
10.1016/j.amjmed.2016.05.012
[Indexed for MEDLINE]

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