Send to

Choose Destination
See comment in PubMed Commons below
Neurosci Lett. 1989 May 8;99(3):257-62.

Induction of neurite outgrowth from chick embryonic ganglia explants by activators of protein kinase C.

Author information

  • 1Department of Biology, Seton Hall University, South Orange, NJ 07079.


Neurite outgrowth from chick embryonic sensory ganglia explants was induced by activators of protein kinase C and other compounds known to stimulate the hydrolysis of inositol phospholipids. The addition of diacylglycerols, phospholipase C and muscarine chloride to a defined growth medium promoted the outgrowth of dense neurites from ganglia explants which were morphologically distinct from those induced by the phorbol ester TPA. Moreover, these neurite-promoting agents did not enhance non-neuronal cell proliferation and were ineffective in the absence of insulin and/or progesterone.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center