Send to

Choose Destination
Int J Sports Med. 2016 Aug;37(9):723-9. doi: 10.1055/s-0042-104935. Epub 2016 Jun 3.

Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes.

Author information

Cardiovascular Health Program, Centro de Salud Familiar, Los Lagos, Chile.
Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile.
Department of Physical Education and Recreation, Faculty of Education, Social Sciences and Humanities, Universidad de la Frontera, Temuco, Chile.
Department of Human Movement Science, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Department of Physiology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria, Australia.
Rehabilitation, Public Hospital of Los Lagos, Los Lagos, Chile.
Exercise and Chronic Disease Research Laboratory, Physical Education Department, School of Sciences, São Paulo State Univiersity - UNESP.


Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5±1.8 years; BMI=30.5±0.6 kg/m(2)) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3±1.4%), HbA1c (12.8±1.1%), systolic blood pressure (3.7±0.5 mmHg), HDL-cholesterol (21.1±2.8%), triglycerides (17.7±2.8%), endurance performance (9.8±1.0%), body weight (2.2±0.3%), BMI (2.1±0.3%), waist circumference (4.0±0.5%) and subcutaneous fat (18.6±1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Georg Thieme Verlag Stuttgart, New York
Loading ...
Support Center