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Pediatr Infect Dis J. 2016 Oct;35(10):1156-9. doi: 10.1097/INF.0000000000001252.

Subdural Empyema Caused by Neisseria meningitidis: A Case Report and Review of the Literature.

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From the *Littlewoods Neurosciences Unit, Alder Hey Children's NHS Foundation Trust; †Institute of Infection and Global Health, University of Liverpool; ‡Department of Paediatric Infectious Diseases and Immunology, §Department of Radiology, ¶Department of Paediatric Neurosurgery, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom; ‖Department of Paediatrics, Wrexham Maelor Hospital, Wrexham, United Kingdom; **Walton Centre NHS Foundation Trust; and ††National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.


Subdural empyema complicating meningococcal meningitis is rare. We describe a case and 14 previously reported cases; all had persistent fever and 12 had seizures. Initial cerebrospinal fluid showed raised protein with low glucose values. Neuroimaging confirmed the diagnosis in all cases where undertaken. Ten children had neurosurgical intervention. Clinical outcome was available in 14 cases; a full recovery was reported in 10 and 1 child died.

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