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Lupus. 2016 Jul;25(8):797-804. doi: 10.1177/0961203316640920.

Report on the second International Consensus on ANA Pattern (ICAP) workshop in Dresden 2015.

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Department of Oral Biology, University of Florida, Gainesville, Florida, USA
Central Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, The Netherlands.
Pontifícia Universidade Católica de Goiás, Goiânia, GO, Brazil.
Laboratory of Immunology, Hospital Carlos G. Durand, and Department of Immunology, Instituto Universitario del Hospital Italiano, Buenos Aires, Argentina.
Institute of Immunology, Technical University of Dresden, Dresden, Germany.
Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Department of Immunology and Rheumatology, Hospital General de Occidente and University of Guadalajara, Guadalajara, Mexico.
Department of Internal Medicine VI, Medical University of Innsbruck, Innsbruck, Austria.
Department of the Control for Rheumatic Diseases and Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Department of Clinical Nursing, University of Occupational and Environmental Health, Kitakyushu, Japan.
Brazilian Society of Autoimmunity, Porto Alegre, Brazil.
Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo; Immunology Division, Fleury Medicine and Health Laboratories, São Paulo, Brazil.


The second meeting for the International Consensus on Antinuclear antibody (ANA) Pattern (ICAP) was held on 22 September 2015, one day prior to the opening of the 12th Dresden Symposium on Autoantibodies in Dresden, Germany. The ultimate goal of ICAP is to promote harmonization and understanding of autoantibody nomenclature, and thereby optimizing ANA usage in patient care. The newly developed ICAP website was introduced to the more than 50 participants. This was followed by several presentations and discussions focusing on key issues including the two-tier classification of ANA patterns into competent-level versus expert-level, the consideration of how to report composite versus mixed ANA patterns, and the necessity for developing a consensus on how ANA results should be reported. The need to establish on-line training modules to help users gain competency in identifying ANA patterns was discussed as a future addition to the website. To advance the ICAP goal of promoting wider international participation, it was agreed that there should be a consolidated plan to translate consensus documents into other languages by recruiting help from members of the respective communities.


Antinuclear antibodies; autoantibodies; autoimmunity; consensus; standardization

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