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Zebrafish. 2016 Jul;13 Suppl 1:S153-63. doi: 10.1089/zeb.2016.1286. Epub 2016 Jun 1.

Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus.

Author information

1
1 Research Oversight and Compliance Office, University of Toronto , Toronto, Canada .
2
2 Zebrafish Genetics and Disease Models Core Facility, Hospital for Sick Children , Toronto, Canada .
3
3 Division of Comparative Medicine, University of Toronto , Toronto, Canada .
4
4 Department of Cell and Systems Biology, University of Toronto , Toronto, Canada .
5
5 Environmental Health and Safety, University of Toronto , Toronto, Canada .
6
6 Department of Biological Sciences, Centre for Prions and Protein Folding Disease, University of Alberta , Edmonton, Canada .
7
7 Department of Biology, University of Ottawa , Ottawa, Canada .
8
8 Department of Anatomy and Cell Biology, University of Saskatchewan , Saskatoon, Canada .
9
9 Department of Cell Biology and Anatomy, Alberta Children's Hospital Research Institute, University of Calgary , Calgary, Canada .
10
10 Department of Medical Genetics, Alberta Children's Hospital Research Institute, University of Calgary , Calgary, Canada .
11
11 Department of Psychology, University of Toronto at Mississauga , Toronto, Canada .
12
12 Department of Biological Sciences, University of Toronto at Scarborough , Toronto, Canada .
13
13 Program in Developmental and Stem Cell Biology, Department of Molecular Genetics, University of Toronto , Toronto, Canada .
14
14 Program in Genetics and Genome Biology, Department of Molecular Genetics, University of Toronto , Toronto, Canada .
15
15 Department of Medicine, Zebrafish Centre for Advanced Drug Discovery, St. Michael's Hospital, University of Toronto , Toronto, Canada .
16
16 Department of Biological Sciences, University of Alberta , Alberta, Canada .
17
17 Department of Neuroscience, The University of Montreal Hospital Research Centre (CRCHUM) , Université de Montréal, Montréal, Canada .
18
18 Office of the Vice-President (Research), University of Alberta , Alberta, Canada .
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19 Risk Management Services, University of Alberta , Alberta, Canada .
20
20 Protective Services and Safety Resources, University of Saskatchewan , Saskatchewan, Canada .
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21 Office of the Vice-President (Research), University of Calgary , Calgary, Canada .
22
22 Environment, Health and Safety, University of Calgary , Calgary, Canada .
23
23 Department of Biology, McMaster University , Hamilton, Canada .
24
24 Office of Risk Management, University of Ottawa , Ottawa, Canada .

Abstract

The zebrafish model system is helping researchers improve the health and welfare of people and animals and has become indispensable for advancing biomedical research. As genetic engineering is both resource intensive and time-consuming, sharing successfully developed genetically modified zebrafish lines throughout the international community is critical to research efficiency and to maximizing the millions of dollars in research funding. New restrictions on importation of zebrafish into Canada based on putative susceptibility to infection by the spring viremia of carp virus (SVCV) have been imposed on the scientific community. In this commentary, we review the disease profile of SVCV in fish, discuss the findings of the Canadian government's scientific assessment, how the interpretations of their assessment differ from that of the Canadian research community, and describe the negative impact of these regulations on the Canadian research community and public as it pertains to protecting the health of Canadians.

PMID:
27248438
DOI:
10.1089/zeb.2016.1286
[Indexed for MEDLINE]

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