Format

Send to

Choose Destination
Trends Parasitol. 2016 Sep;32(9):664-666. doi: 10.1016/j.pt.2016.05.006. Epub 2016 May 24.

Helminths and Intestinal Flora Team Up to Improve Gut Health.

Author information

1
Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia. Electronic address: paul.giacomin@jcu.edu.au.
2
Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.

Abstract

Inflammatory bowel diseases (IBD) are associated with impaired intestinal barrier function, chronic inflammation, and microbial dysbiosis. In a recent publication in Science, Ramanan et al. used murine and human studies to demonstrate that infections with gastrointestinal helminths can protect against IBD by provoking immune responses that alter the balance of commensal and pathogenic bacteria in the intestine.

KEYWORDS:

helminth; hygiene hypothesis; inflammatory bowel disease.; microbiota

PMID:
27234811
DOI:
10.1016/j.pt.2016.05.006
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center