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Nat Cell Biol. 2016 May 27;18(6):591-2. doi: 10.1038/ncb3366.

Primary cilia mechanosensing triggers autophagy-regulated cell volume control.

Author information

1
Interfaculty Institute of Cell Biology, Eberhard Karls University Tübingen, and the International Max Planck Research School 'From Molecules to Organisms', Tübingen, Germany.

Abstract

The primary cilium and the process of autophagy are thought to be in a functionally reciprocal relationship. In further support of this link, fluid flow sensing by the primary cilium is now shown to induce autophagy, which in turn regulates the volume of kidney epithelial cells.

PMID:
27230529
DOI:
10.1038/ncb3366
[Indexed for MEDLINE]

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