Successful treatment continuation with a single mild partial splenic embolization for thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced colon cancer

Joichi Heianna; Osamu Muto; Takaharu Miyauchi; Wataru Endo; Aki Togashi; Kimei Azama; Sadayuki Murayama

doi:10.1007/s12664-016-0665-9

Successful treatment continuation with a single mild partial splenic embolization for thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced colon cancer

Indian J Gastroenterol. 2016 May;35(3):245-7. doi: 10.1007/s12664-016-0665-9. Epub 2016 May 27.

Authors

Joichi Heianna¹, Osamu Muto², Takaharu Miyauchi³, Wataru Endo³, Aki Togashi³, Kimei Azama⁴, Sadayuki Murayama⁴

Affiliations

¹ Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207, Uehara, Nishihara, Okinawa, 903-0215, Japan. anna1150@med.u-ryukyu.ac.jp.
² Department of Clinical Oncology, Akita Red Cross Hospital, 222-1, Kamikitate, Saruta, Akita City, 010-1406, Japan.
³ Department of Radiology, Akita Red Cross Hospital, 222-1, Kamikitate, Saruta, Akita City, 010-1406, Japan.
⁴ Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207, Uehara, Nishihara, Okinawa, 903-0215, Japan.

PMID: 27230031
DOI: 10.1007/s12664-016-0665-9

Abstract

We report the case of a patient with advanced colon cancer receiving oxaliplatin-based chemotherapy that was able to continue systemic chemotherapy by performing mild partial splenic embolization (PSE) for thrombocytopenia caused by splenomegaly due to oxaliplatin. Mild PSE may be useful for thrombocytopenia due to splenomegaly in cancer patients because it provides more treatment opportunities.

Keywords: Colon cancer; Oxaliplatin; Partial splenic embolization; Splenomegaly; Thrombocytopenia.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Colonic Neoplasms / drug therapy*
Embolization, Therapeutic / methods*
Female
Humans
Organoplatinum Compounds / administration & dosage
Organoplatinum Compounds / adverse effects*
Oxaliplatin
Spleen*
Splenomegaly / chemically induced
Thrombocytopenia / chemically induced*
Thrombocytopenia / therapy*
Treatment Outcome

Substances

Organoplatinum Compounds
Oxaliplatin