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Magn Reson Med. 2017 May;77(5):2066-2076. doi: 10.1002/mrm.26287. Epub 2016 May 25.

Resolving phase ambiguity in dual-echo dixon imaging using a projected power method.

Author information

1
Department of Radiology, Stanford University, Stanford, California, USA.
2
Department of Electrical Engineering, Stanford University, Stanford, California, USA.
3
Department of Electrical Engineering, Princeton University, Princeton, New Jersey, USA.

Abstract

PURPOSE:

To develop a fast and robust method to resolve phase ambiguity in dual-echo Dixon imaging.

METHODS:

A major challenge in dual-echo Dixon imaging is to estimate the phase error resulting from field inhomogeneity. In this work, a binary quadratic optimization program was formulated to resolve the phase ambiguity. A projected power method was developed to efficiently solve the optimization problem. Both the 1-peak fat model and 6-peak fat model were applied to three-dimensional (3D) datasets. Additionally, the proposed method was extended to dynamic magnetic resonance imaging (MRI) applications using the 6-peak fat model. With institutional review board (IRB) approval and patient consent/assent, the proposed method was evaluated and compared with region growing on 29 consecutive 3D high-resolution patient datasets.

RESULTS:

Fast and robust water/fat separation was achieved by the proposed method in different representative 3D datasets and dynamic 3D datasets. Superior water/fat separation was achieved using the 6-peak fat model compared with the 1-peak fat model. Compared to region growing, the proposed method reduced water/fat swaps from 76 to 7% of the patient cohort.

CONCLUSION:

The proposed method can achieve fast and robust phase error estimation in dual-echo Dixon imaging. Magn Reson Med 77:2066-2076, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

KEYWORDS:

binary quadratic optimization; dynamic Dixon; fat suppression; two-point Dixon; water-fat separation

PMID:
27221766
PMCID:
PMC5123983
DOI:
10.1002/mrm.26287
[Indexed for MEDLINE]
Free PMC Article

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