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Talanta. 2016 Aug 1;155:14-20. doi: 10.1016/j.talanta.2016.04.021. Epub 2016 Apr 11.

One-pot aqueous synthesis of gadolinium doped CdTe quantum dots with dual imaging modalities.

Author information

1
Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China.
2
College of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, PR China.
3
Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China. Electronic address: hpeng@ee.ecnu.edu.cn.

Abstract

A facile one-pot strategy has been developed for the aqueous synthesis of Gd doped CdTe (Gd:CdTe) QDs as fluorescence and magnetic resonance imaging dual-modal agent. The prepared Gd:CdTe QDs showed narrow size distribution and the average size was less than 5nm. The amount of Gd(3+) dopant in Gd:CdTe QDs significantly affected the optical properties of obtained QDs. The highest PL QY for the prepared Gd:CdTe QDs was up to 42.5%. The QDs showed the weak toxicity and significant enhancement in MRI signal. The specific relaxivity value (r1) was determined to be 4.22mM(-1)s(-1). These properties make the prepared Gd:CdTe QDs be an effective dual-modal imaging agent and have great potential applications in biomedical field.

KEYWORDS:

Aqueous synthesis; Fluorescence; Gd doped CdTe; MR imaging; Quantum dots

PMID:
27216651
DOI:
10.1016/j.talanta.2016.04.021
[Indexed for MEDLINE]

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