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NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met).
Nat Chem Biol. 2016 Jul;12(7):546-51. doi: 10.1038/nchembio.2099. Epub 2016 May 23.
Nat Chem Biol. 2016.
PMID: 27214402
Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Van Haute L, Dietmann S, Kremer L, Hussain S, Pearce SF, Powell CA, Rorbach J, Lantaff R, Blanco S, Sauer S, Kotzaeridou U, Hoffmann GF, Memari Y, Kolb-Kokocinski A, Durbin R, Mayr JA, Frye M, Prokisch H, Minczuk M.
Van Haute L, et al.
Nat Commun. 2016 Jun 30;7:12039. doi: 10.1038/ncomms12039.
Nat Commun. 2016.
PMID: 27356879
Free PMC article.
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NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation.
Haag S, Sloan KE, Ranjan N, Warda AS, Kretschmer J, Blessing C, Hübner B, Seikowski J, Dennerlein S, Rehling P, Rodnina MV, Höbartner C, Bohnsack MT.
Haag S, et al.
EMBO J. 2016 Oct 4;35(19):2104-2119. doi: 10.15252/embj.201694885. Epub 2016 Aug 5.
EMBO J. 2016.
PMID: 27497299
Free PMC article.
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