Format

Send to

Choose Destination
Carcinogenesis. 1989 Jun;10(6):1085-7.

Structure of a mutagen from roasted seeds of Moringa oleifera.

Author information

1
Institute of Chemistry, University of the Philipines, Diliman, Quezon City.

Abstract

A mutagenic compound was isolated from roasted seeds of Moringa oleifera Lam. Its structure has been elucidated by spectral analysis as 4(alpha-L-rhamnosyloxy)phenylacetonitrile. The results of the Micronucleus Test, an in vivo method, showed that the number of micronucleated polychromatic erythrocytes (PCE)/1000 PCE for this compound is higher than that of the solvent control, dimethylsulfoxide, and approximates that of the positive control, tetracycline. This indicates that 4(alpha-L-rhamnosyloxy)phenylacetonitrile is a genotoxic compound.

PMID:
2720902
DOI:
10.1093/carcin/10.6.1085
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center