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Trends Biotechnol. 2016 Oct;34(10):810-824. doi: 10.1016/j.tibtech.2016.04.008.

Biomedical Applications of Terahertz Spectroscopy and Imaging.

Author information

1
Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
2
Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
3
Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address: fwl@tmmu.edu.cn.
4
Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address: luoyang@tmmu.edu.cn.

Abstract

Terahertz (THz=10(12)Hz) radiation has attracted wide attention for its unprecedented sensing ability and its noninvasive and nonionizing properties. Tremendous strides in THz instrumentation have prompted impressive breakthroughs in THz biomedical research. Here, we review the current state of THz spectroscopy and imaging in various biomedical applications ranging from biomolecules, including DNA/RNA, amino acids/peptides, proteins, and carbohydrates, to cells and tissues. We also address the potential biological effects of THz radiation during its biological applications and propose future prospects for this cutting-edge technology.

KEYWORDS:

THz; biological effect; biomedical research; imaging; spectroscopy; terahertz

PMID:
27207226
DOI:
10.1016/j.tibtech.2016.04.008
[Indexed for MEDLINE]

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