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Tech Coloproctol. 2016 Aug;20(8):551-7. doi: 10.1007/s10151-016-1491-x. Epub 2016 May 19.

Treatment of irritable bowel syndrome with a novel colonic irrigation system: a pilot study.

Author information

1
Division of Colorectal Surgery, Department of Surgery, Mackay Memorial Hospital, 92, Sec. 2, Zhongshan N. Rd., Taipei City, 10449, Taiwan.
2
Division of Colorectal Surgery, Department of Surgery, Mackay Memorial Hospital, 92, Sec. 2, Zhongshan N. Rd., Taipei City, 10449, Taiwan. leungwh22@gmail.com.
3
Department of Rehabilitation Medicine, Mackay Memorial Hospital, Taipei City, Taiwan.

Abstract

BACKGROUND:

Medical treatments for irritable bowel syndrome (IBS) are often disappointing. A colonic irrigation system, the Ashong colonic irrigation apparatus (ACIA), was designed as a patient-administered device for defecation disorders. This pilot study evaluated the efficacy and safety of ACIA for IBS.

METHODS:

Eighteen patients, 12 with constipation-dominant IBS (IBS-C) and 6 with diarrhea-dominant IBS (IBS-D) group, were studied. Patients were randomized into treatments of 1-4 weeks. Colonic irrigation was performed twice daily for 6 consecutive days per week. To determine the response to treatment, bowel movement frequency, stool consistency, abdominal pain, patient satisfaction with bowel movements, and distress/discomfort due to symptoms were assessed.

RESULTS:

The scores of abdominal pain (p < 0.001), satisfaction (p < 0.001), and distress/discomfort (p < 0.001) improved significantly. The frequency of bowel movements in the IBS-C group increased from 1.68 to 3.78 times per week (p < 0.001). The occurrence of Bristol Stool Scale type 1 and 2 stool passage decreased from 45 to 13 % (p = 0.009) in the IBS-C group and type 6 and 7 stools decreased from 62 to 28 % (p = 0.005) in the IBS-D group. Only mild adverse events occurred, and all patients completed treatment.

CONCLUSIONS:

Colonic irrigation with ACIA is safe and can improve abdominal pain, constipation, and diarrhea associated with IBS. Patients were more satisfied with their bowel movements and found their symptoms were less disturbing. Larger studies on long-term efficacy and quality of life and on placebo effects are needed.

KEYWORDS:

Ashong colonic irrigation apparatus; Colonic irrigation; Irritable bowel syndrome

PMID:
27194235
PMCID:
PMC4960275
DOI:
10.1007/s10151-016-1491-x
[Indexed for MEDLINE]
Free PMC Article

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