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J Craniomaxillofac Surg. 2016 Jul;44(7):800-10. doi: 10.1016/j.jcms.2016.04.013. Epub 2016 Apr 16.

Implant supported dental rehabilitation following segmental mandibular reconstruction- quality of life outcomes of a prospective randomized trial.

Author information

1
Head and Neck Institute, Mazumdar Shaw Cancer Center, Narayana Health, Bommasandra, Bangalore, India; Department of Oral and Maxillofacial Surgery-Plastic Surgery, University Medical Center of Johannes Gutenberg University, Mainz, Germany. Electronic address: veezo@rediffmail.com.
2
Head and Neck Institute, Mazumdar Shaw Cancer Center, Narayana Health, Bommasandra, Bangalore, India. Electronic address: pcjacob66@gmail.com.
3
Department of Periodontics, M. R. Ambedkar Dental College & Hospital, Bangalore, India. Electronic address: supriyaebenezer@gmail.com.
4
Head and Neck Institute, Mazumdar Shaw Cancer Center, Narayana Health, Bommasandra, Bangalore, India. Electronic address: makuriakose@gmail.com.
5
Head and Neck Institute, Mazumdar Shaw Cancer Center, Narayana Health, Bommasandra, Bangalore, India. Electronic address: kvikram2000@gmail.com.
6
Department of Plastic and Reconstructive Surgery (Head: Prof. Dr. A. S. Baliarsing), BYL Nair Charitable Hospital and Topiwala National Medical College, Mumbai, India. Electronic address: amresh_baliarsing@hotmail.com.
7
Department of Oral and Maxillofacial Surgery-Plastic Surgery, University Medical Center of Johannes Gutenberg University, Mainz, Germany. Electronic address: Al-Nawas@uni-mainz.de.
8
Department of Oral and Maxillofacial Surgery-Plastic Surgery, University Medical Center of Johannes Gutenberg University, Mainz, Germany. Electronic address: wilfried.wagner@unimedizin-mainz.de.

Abstract

PURPOSE:

The primary objective of this study was to assess the difference in quality of life (QoL) in patients with dental rehabilitation using two or four implant-supported overdentures following segmental mandibulectomy defect reconstruction with fibula free flap.

MATERIAL AND METHODS:

This prospective, parallel designed, randomized clinical study was conducted with a 1:1 ratio. At baseline, all participants already had fibula flap reconstruction for segmental defects of the mandible and rehabilitation with conventional (non-implant supported) removable partial dentures. The participants were then randomized into two groups. Group I received implant supported overdentures on two implants, and Group II received four implants. QoL outcomes were evaluated using standardized questionnaires (EORTC_QLQ c30, H&N35, OHIP, DSI). Outcomes of treatment were evaluated at 6 months (T1) and 1 year (T2) following rehabilitation.

RESULTS:

A total of 52 patients were randomized into two treatment groups (26 each). After accounting for the loss to lack of follow-up, 22 patients in Group I and 24 patients in Group II were evaluated for QoL at the end of the study. There was a significant improvement in QoL with implant-assisted dental rehabilitation. However there were no significant differences in QoL between the two-implant and four-implant groups.

CONCLUSION:

Implant-supported removable overdentures improve QoL outcomes in patients with reconstructed mandibles. This study showed no significant difference in QoL outcomes in patients with two- or four-implant supported removable prostheses.

KEYWORDS:

Dental implants; Free fibula flap; Mandible reconstruction; Oral cancer; Quality of life; Rehabilitation

PMID:
27193480
DOI:
10.1016/j.jcms.2016.04.013
[Indexed for MEDLINE]

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