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Curr Allergy Asthma Rep. 2016 Jun;16(6):43. doi: 10.1007/s11882-016-0622-9.

Indoor Allergens and Allergic Respiratory Disease.

Author information

1
Indoor Biotechnologies, Inc., 700 Harris Street, Charlottesville, VA, 22903, USA. apomes@inbio.com.
2
Indoor Biotechnologies, Inc., 700 Harris Street, Charlottesville, VA, 22903, USA.

Abstract

PURPOSE OF REVIEW:

The purpose of this review is to evaluate the most recent findings on indoor allergens and their impact on allergic diseases.

RECENT FINDINGS:

Indoor allergens are present inside buildings (home, work environment, school), and given the chronic nature of the exposures, indoor allergies tend to be associated with the development of asthma. The most common indoor allergens are derived from dust mites, cockroaches, mammals (including wild rodents and pets), and fungi. The advent of molecular biology and proteomics has led to the identification, cloning, and expression of new indoor allergens, which have facilitated research to elucidate their role in allergic diseases. This review is an update on new allergens and their molecular features, together with the most recent reports on their avoidance for allergy prevention and their use for diagnosis and treatment. Research progress on indoor allergens will result in the development of new diagnostic tools and design of coherent strategies for immunotherapy.

KEYWORDS:

Cat; Cockroach; Dog; Fungi; Indoor allergens; Mite

PMID:
27184001
PMCID:
PMC4976688
DOI:
10.1007/s11882-016-0622-9
[Indexed for MEDLINE]
Free PMC Article

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