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Curr Bladder Dysfunct Rep. 2016 Mar;11(1):18-24. Epub 2016 Jan 30.

The bladder is not sterile: History and current discoveries on the urinary microbiome.

Author information

1
Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University, Chicago, Illinois, USA.
2
Departments of Obstetrics & Gynecology and Urology, Loyola University Medical Center, Maywood, Illinois, USA.
3
Associate Professor, Departments of Obstetrics and Gynecology and Urology, Division of Female Pelvic Medicine and Reconstructive Surgery, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153, , FAX: (708) 216-4305.

Abstract

In the human body, there are 10 bacterial cells for every one human cell. This fact highlights the importance of the National institutes of Health's initiative to map the human microbiome. The Human Microbiome Project was the first large-scale mapping of the human microbiome of 5 body sites: GI tract, mouth, vagina, skin and nasal cavity using culture-independent methods. The bladder was not originally tested because it was considered to be sterile and there were complexities regarding sample collection. Over the last couple years our team along with other investigators have shown that a urinary microbiome exists and for most individuals it plays a protective role.

KEYWORDS:

Urinary microbiome; bacteria; urgency incontinence

PMID:
27182288
PMCID:
PMC4864995
[Available on 2017-03-01]
DOI:
10.1007/s11884-016-0345-8

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