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Circ J. 2016 May 25;80(6):1285-91. doi: 10.1253/circj.CJ-16-0326. Epub 2016 May 13.

Catecholaminergic Polymorphic Ventricular Tachycardia.

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Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Centre.


Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia disorder that is characterized by emotion- and exercise-induced polymorphic ventricular arrhythmias and may lead to sudden cardiac death (SCD). CPVT plays an important role in SCD in the young and therefore recognition and adequate treatment of the disease are of vital importance. In the past years tremendous improvements have been made in the diagnostic methods and treatment of the disease. In this review, we summarize the clinical characteristics, genetics, and diagnostic and therapeutic strategies of CPVT and describe the most recent advances and some of the current challenges. (Circ J 2016; 80: 1285-1291).

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