Format

Send to

Choose Destination
Clin Cardiol. 2016 Aug;39(8):459-63. doi: 10.1002/clc.22549. Epub 2016 May 13.

In Hypertrophic Cardiomyopathy, the Spatial Peaks QRS-T Angle Identifies Those With Sustained Ventricular Arrhythmias.

Author information

1
Department of Pediatric Cardiology, Children's Hospital of Colorado/University of Colorado, Aurora, Colorado.
2
Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden.
3
Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado.

Abstract

BACKGROUND:

The spatial peaks QRS-T (SPQRS-T) angle differentiates hypertrophic cardiomyopathy (HCM) patients from controls. Increased angle confers arrhythmia risk in other populations.

HYPOTHESIS:

We predict that the SPQRS-T angle will identify HCM patients with sustained ventricular arrhythmias (VAs) and those with New York Heart Association class III/IV heart failure.

METHODS:

Corrected QT interval, QRS duration, and SPQRS-T angle were assessed in HCM patients with VAs (>30 seconds) and those without VAs.

RESULTS:

One hundred HCM patients (mean age, 32.7 ± 17.2 years) were assessed. Twenty patients had VAs. The corrected QT interval identified VA (P = 0.018) and at 460 ms gave positive and negative predictive values of 28.6% and 83.3%, respectively, and an odds ratio of 2.0 (95% confidence interval: 0.7-5.6). The SPQRS-T angle differentiated VA from no VA (P < 0.001) and at 124.1 degrees gave positive and negative predictive values and an odds ratio of 36.7%, 96.1%, and 14.2 (95% confidence interval: 3.1-65.6), respectively.

CONCLUSIONS:

The SPQRS-T angle best differentiated patients with VAs.

PMID:
27175825
DOI:
10.1002/clc.22549
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center