Send to

Choose Destination
See comment in PubMed Commons below
J Sports Sci. 2017 Apr;35(7):663-668. doi: 10.1080/02640414.2016.1183807. Epub 2016 May 12.

Exercise coupled with dietary restriction reduces oxidative stress in male adolescents with obesity.

Li C1,2, Feng F1, Xiong X1, Li R1, Chen N1,2.

Author information

a Hubei Key Laboratory of Exercise Training and Monitoring, College of Health Science , Wuhan Sports University , Wuhan , China.
b Hubei Provincial Collaborative Innovation Center for Exercise and Health Promotion , Wuhan Sports University , Wuhan , China.


The increased oxidative stress is usually observed in obese population, but the control of body weight by calorie restriction and/or exercise training can ameliorate oxidative stress. In order to evaluate oxidative stress in response to exercise and dietary restriction in obese adolescents, a total of 20 obese volunteers were enrolled in a 4-week intervention program including exercise training and dietary restriction. Body compositions and blood samples were analysed before and after 4-week intervention, and biomarkers associated with oxidative stress were examined. After 4-week exercise training coupled with dietary restriction, physical composition parameters including body mass, body mass index (BMI), lean body mass, body fat mass and fat mass ratio had obvious reduction by 12.43%, 13.51%, 5.83%, 25.05% and 14.52%, respectively. In addition, the activities of antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) revealed a remarkable enhancement. On the other hand, protein carbonyls (PC) exhibited an obvious reduction. Moreover, total thiols and nitrites with respect to baseline revealed a reducing trend although no significant difference was observed. Therefore, the 4-week exercise intervention coupled with dietary restriction is benefit for the loss of body weight and the mitigation of oxidative stress in obese population so that it can be a recommendable intervention prescription for the loss of body weight.


Oxidative stress; body weight loss; diet restriction; exercise intervention; obesity

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center