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PLoS One. 2016 May 11;11(5):e0155182. doi: 10.1371/journal.pone.0155182. eCollection 2016.

Risk of Vaginal Infections at Early Gestation in Patients with Diabetic Conditions during Pregnancy: A Retrospective Cohort Study.

Author information

1
Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetomaternal Medicine at the Medical University Vienna, Vienna, Austria.
2
Section for Medical Statistics (IMS), Centre of Medical Statistics, Informatics and Intelligent Systems at the Medical University Vienna, Vienna, Austria.

Abstract

Pregnant women with gestational diabetes mellitus (GDM) are reported to be at increased risk for infections of the genital tract. This study aimed to compare the prevalence of asymptomatic bacterial vaginosis (BV) and Candida colonization at early gestation between pregnant women with and without diabetic conditions during pregnancy. We included data from 8, 486 singleton pregnancies that underwent an antenatal infection screen-and-treat programme at our department. All women with GDM or pre-existing diabetes were retrospectively assigned to the diabetic group (DIAB), whereas non-diabetic women served as controls (CON). Prevalence for BV and Candida colonization was 9% and 14% in the DIAB group, and 9% and 13% in the CON group, respectively (n.s.). No significant difference regarding stillbirth and preterm delivery (PTD), defined as a delivery earlier than 37 + 0 (37 weeks plus 0 days) weeks of gestation was found. We could not find an increased risk of colonization with vaginal pathogens at early gestation in pregnant women with diabetes, compared to non-diabetic women. Large prospective studies are needed to evaluate the long-term risk of colonization with vaginal pathogens during the course of pregnancy in these women.

PMID:
27167850
PMCID:
PMC4864213
DOI:
10.1371/journal.pone.0155182
[Indexed for MEDLINE]
Free PMC Article

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