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Trends Parasitol. 2016 Jul;32(7):554-564. doi: 10.1016/j.pt.2016.04.009. Epub 2016 May 4.

Rickettsia felis: The Complex Journey of an Emergent Human Pathogen.

Author information

1
URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Aix Marseille Université, 27 Bd Jean Moulin, 13385 Marseille, France. Electronic address: angelotasmanos@msn.com.
2
URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Aix Marseille Université, 27 Bd Jean Moulin, 13385 Marseille, France.

Abstract

Rickettsia felis is an obligate intracellular bacterium that is different from other officially recognized rickettsial species. It has multiple genes of different origins, an incubation temperature of less than 32°C, and a conjugative plasmid. This Rickettsia is commonly detected in febrile patients in sub-Saharan Africa. R. felis is frequently detected in cat fleas, but recently mosquitoes have been suspected to be able to transmit the bacterium. However, many aspects of the ecology and epidemiology of R. felis are not completely understood and remain to be uncovered. We aim here to give an update of the current knowledge about this fascinating organism.

KEYWORDS:

Rickettsia felis; flea-borne spotted fever; rickettsial infections

PMID:
27155905
DOI:
10.1016/j.pt.2016.04.009
[Indexed for MEDLINE]

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