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Bioinformatics. 2016 Jun 15;32(12):1903-4. doi: 10.1093/bioinformatics/btw098. Epub 2016 Feb 18.

Coala: an R framework for coalescent simulation.

Author information

1
Department of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried 82152, Germany.

Abstract

Simulation programs based on the coalescent efficiently generate genetic data according to a given model of evolution. We present coala, an R package for calling coalescent simulators with a unified syntax. It can execute simulations with several programs, calculate additional summary statistics and combine multiple simulations to create biologically more realistic data.

AVAILABILITY AND IMPLEMENTATION:

The package is publicly available on CRAN and on https://github.com/statgenlmu/coala under the conditions of the MIT license.

CONTACT:

metzler@bio.lmu.de.

PMID:
27153679
DOI:
10.1093/bioinformatics/btw098
[Indexed for MEDLINE]

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