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Cell Stem Cell. 2016 May 5;18(5):559-60. doi: 10.1016/j.stem.2016.04.009.

Understanding How Zika Virus Enters and Infects Neural Target Cells.

Author information

1
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
2
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: diamond@borcim.wustl.edu.

Abstract

Zika virus is a mosquito-transmitted flavivirus that has become a public health concern because of its ability to cause microcephaly. In this issue of Cell Stem Cell, Tang et al. (2016) and Nowakowski et al. (2016) use human neural stem cell models and single-cell RNA sequencing to investigate Zika virus tropism and potential entry receptors.

PMID:
27152436
DOI:
10.1016/j.stem.2016.04.009
[Indexed for MEDLINE]
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