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Genome Announc. 2016 May 5;4(3). pii: e00337-16. doi: 10.1128/genomeA.00337-16.

Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology.

Author information

1
Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico, USA.
2
National Center for Genome Resources (NCGR), Santa Fe, New Mexico, USA.
3
National Center for Genome Resources (NCGR), Santa Fe, New Mexico, USA Department of Biology, University of New Mexico, Albuquerque, New Mexico, USA.
4
Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico, USA Department of Biology, University of New Mexico, Albuquerque, New Mexico, USA Center for Biomedical Engineering, University of New Mexico, Albuquerque, New Mexico, USA cemelanc@unm.edu.

Abstract

Here, we report the complete genome sequence of Streptomyces venezuelae ATCC 15439, a producer of the methymycin/pikromycin family of macrolide antibiotics and a model host for natural product studies, obtained exclusively using PacBio sequencing technology. The 9.03-Mbp genome harbors 8,775 genes and 11 polyketide and nonribosomal peptide natural product gene clusters.

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