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Hipertens Riesgo Vasc. 2016 Oct - Dec;33(4):155-158. doi: 10.1016/j.hipert.2016.03.002. Epub 2016 Apr 15.

[Primary hyperaldosteronism due to unilateral adrenal hyperplasia with surgical resolution].

[Article in Spanish]

Author information

1
Servicio de Endocrinología y Nutrición, Hospital General Universitario de Castellón, Castellón, España. Electronic address: olallarubio@gmail.com.
2
Servicio de Endocrinología y Nutrición, Hospital Universitario Doctor Peset, Valencia, España.
3
Servicio de Endocrinología y Nutrición, Hospital Universitario Doctor Peset, Valencia, España; Departamento de Medicina, Universidad de Valencia, Valencia, España; Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Valencia, España.

Abstract

Unilateral adrenal hyperplasia is a rare cause of primary hyperaldosteronism (around a 3%) that has surgical treatment. A case of a patient with hypertension resistant to conventional therapy in treatment with 7 drugs who presented with primary hyperaldosteronism due to unilateral adrenal hyperplasia is presented. A left adrenalectomy was performed, and the patient had a good clinical response, with no need of any drug after 2 years of surgery. Unilateral adrenal hyperplasia is a different entity and it is not an asymmetric variant of the bilateral adrenal hyperplasia. In the study of patients with primary hyperaldosteronism and imaging tests with absence of adenoma is a diagnosis that must be considered before cataloguing patients with bilateral adrenal hyperplasia and start a medical treatment, because unilateral adrenal hyperplasia would have a surgical resolution.

KEYWORDS:

Adrenal hyperplasia; Hiperaldosteronismo; Hiperplasia adrenal; Hipertensión resistente; Hyperaldosteronism; Hypertension resistant to conventional therapy

PMID:
27151066
DOI:
10.1016/j.hipert.2016.03.002
[Indexed for MEDLINE]

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