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Fish Shellfish Immunol. 2016 Jul;54:556-63. doi: 10.1016/j.fsi.2016.04.127. Epub 2016 May 3.

Beta-1,3-1,6-glucan modulate the non-specific immune response to enhance the survival in the Vibrio alginolyticus infection of Taiwan abalone (Haliotis diversicolor supertexta).

Author information

1
Institute of Fisheries Science, National Taiwan University, Taipei, 10617, Taiwan.
2
Department of Aquaculture, National Taiwan Ocean University, Keelung, 20248, Taiwan.
3
Department of Aquaculture, National Taiwan Ocean University, Keelung, 20248, Taiwan. Electronic address: fhnan@mail.ntou.edu.tw.

Abstract

This research aims to investigate the non-specific immune response of Taiwan abalone (Haliotis diversicolor supertexta) which was treated with the beta-1,3-1,6-glucan to be observed in the survival impact after the Vibrio alginolyticus infection. The non-specific immune and physiological response of superoxide anion radical (O2(-)), phenoloxidase (PO), phagocytic index (PI), phagocytic rate (PR) and lucigenin-chemiluminescence for reactive oxygen intermediates (ROIs) were enhanced via in-vitro experiment. In the in-vivo experiment, the observed data presented that the haemolymph lysate supernatant (HLS), superoxide dismutase (SOD), glutamate oxalacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) were not significant enhanced, but the total haemocyte count (THC), O2(-), PO, phagocytic index (PI), phagocytic ratio (PR) and other parameters of immune were significantly promoted after treated with beta-1,3-1,6-glucan. In the challenge experiment, the survival rates of abalone in the 40 and 80 μl/ml groups of beta-1,3-1,6-glucan were observed from 6.67% up to 33.33% and 36.67% after injection with Vibrio alginolyticus, respectively.

KEYWORDS:

Beta-1,3-1,6-glucan; Taiwan abalone; Vibrio alginolyticus

PMID:
27150049
DOI:
10.1016/j.fsi.2016.04.127
[Indexed for MEDLINE]

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