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Int J Food Sci Nutr. 2015 Aug;67(5):571-80. doi: 10.1080/09637486.2016.1181156. Epub 2016 May 5.

Effect of probiotics on body weight and body-mass index: a systematic review and meta-analysis of randomized, controlled trials.

Author information

1
a Department of Endocrinology , Taizhou People's Hospital , Taizhou , China ;
2
b Department of Cardiology , Taizhou People's Hospital , Taizhou , China.

Abstract

OBJECTIVE:

To assess the efficacy of probiotic therapies on body weight and BMI using a meta-analysis of randomized, controlled trials.

METHODS:

Twenty studies with 25 trials (1931 participants with age over 18 years) were included. The pooled WMD was calculated by random effects model.

RESULTS:

Probiotic consumption significantly reduced body weight by 0.59 kg (95% CI, 0.30-0.87) and BMI by 0.49 kg/m(2) (95% CI, 0.24-0.74). A greater reduction in BMI was found with multiple species of probiotics. Subgroup analysis of trials with intervention duration ≥8 weeks found a more significant reduction in BMI. Limiting analysis to trials with a baseline BMI ≥25 kg/m(2) showed a greater reduction in BMI.

CONCLUSION:

Consuming probiotics could reduce body weight and BMI, with a potentially greater effect when multiple species of probiotics were consumed, the duration of intervention was ≥8 weeks, or the objects were overweight.

KEYWORDS:

BMI; meta-analysis; obesity; overweight; probiotics

PMID:
27149163
DOI:
10.1080/09637486.2016.1181156
[Indexed for MEDLINE]

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