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Eur Arch Paediatr Dent. 2016 Jun;17(3):195-203. doi: 10.1007/s40368-016-0229-9. Epub 2016 May 4.

Dental treatment for people with cystic fibrosis.

Author information

1
Department of Paediatric Dentistry, University Dental Hospital Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK. naomiharrington4@gmail.com.
2
Manchester Adult Cystic Fibrosis, University Hospital of South Manchester, Wythenshawe, Manchester, UK.
3
Institute of Inflammation and Repair, University of Manchester, Manchester, UK.
4
Department of Paediatric Dentistry, University Dental Hospital Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK.
5
University of Manchester, Manchester, UK.

Abstract

AIM:

To describe the nature and consequences of the multi-system genetic condition cystic fibrosis with a view to ensuring optimal dental treatment planning for these patients.

METHODS:

A literature search was conducted to identify the key medical and dental manifestations of cystic fibrosis. These findings are discussed and utilised to create recommendations for treatment planning in patients with cystic fibrosis for the practising dental practitioner.

RESULTS:

Cystic fibrosis is a complex, lethal, multisystem autosomal recessive disorder resulting from mutations on chromosome 7 which result in dysfunction of an ion channel that sits on epithelial surfaces. Respiratory disease remains the leading cause of mortality. Survival has greatly increased in recent decades secondary to improved treatment and specialist care. Specific dental manifestations of the disease may result from the condition itself or complications of treatment. Modification of patient management may be necessary to provide optimum patient care.

CONCLUSION:

The pathophysiology and clinical manifestations are relevant to practicing dental practitioners and inform recommendations to be utilised to ensure optimal treatment planning for these patients.

KEYWORDS:

Caries; Cystic fibrosis; Dental; Respiratory

PMID:
27146508
DOI:
10.1007/s40368-016-0229-9
[Indexed for MEDLINE]

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