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Acta Cir Bras. 2016;31 Suppl 1:19-23. doi: 10.1590/S0102-86502016001300005.

Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease.

Author information

1
Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Brazil.
2
School of the Barão, Barão de Mauá University Center, Brazil.
3
São Paulo Hospital, Brazil.

Abstract

PURPOSE:

To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn's disease.

METHODS:

A total of 29 subjects with refractory Crohn's disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn's disease.

RESULTS:

A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn's disease healing rate was 65%.

CONCLUSION:

Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn's disease.

PMID:
27142900
DOI:
10.1590/S0102-86502016001300005
[Indexed for MEDLINE]
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