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Antimicrob Agents Chemother. 2016 Jun 20;60(7):4380-3. doi: 10.1128/AAC.02753-15. Print 2016 Jul.

Detection of Carbapenemase Genes in Aquatic Environments in Rio de Janeiro, Brazil.

Author information

1
Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
2
Departamento de Saneamento e Saúde Ambiental (DSSA), Escola Nacional de Saúde Pública Sérgio Arouca, Fiocruz, Rio de Janeiro, Brazil.
3
Laboratório de Tecnologia Diagnóstica (LATED), Vice-Diretoria de Desenvolvimento Tecnológico (VDTEC), Bio-Manguinhos, Fiocruz, Rio de Janeiro, Brazil.
4
Laboratório de Entomologia Médica e Forense (LEMEF), Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
5
Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil anapdca@ioc.fiocruz.br.

Abstract

This study reveals the presence of different carbapenemase genes (blaKPC, blaNDM, blaGES, and blaOXA48-like genes) detected directly from water samples and clonal dispersion (by pulsed-field gel electrophoresis [PFGE] and multilocus sequence typing [MLST]) of KPC-2-producing Enterobacteriaceae in two important urban aquatic matrixes from Rio de Janeiro, Brazil, highlighting the role of aquatic environments as gene pools and the possibility of community spreading.

PMID:
27139469
PMCID:
PMC4914687
DOI:
10.1128/AAC.02753-15
[Indexed for MEDLINE]
Free PMC Article

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