Send to

Choose Destination
Therap Adv Gastroenterol. 2016 May;9(3):408-16. doi: 10.1177/1756283X16639003. Epub 2016 Mar 21.

The new kid on the block for advanced imaging in Barrett's esophagus: a review of volumetric laser endomicroscopy.

Author information

Division of Gastroenterology, 270-05 76th Ave, 2nd Floor Research Building, Long Island Jewish Medical Center, Hofstra Northwell School of Medicine, Northwell Health System, New Hyde Park, NY 11040, USA.
Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.


Advanced imaging techniques used in the management of Barrett's esophagus include electronic imaging enhancement (e.g. narrow band imaging, flexible spectral imaging color enhancement, and i-Scan), chromoendoscopy, and confocal laser endomicroscopy. Electronic imaging enhancement is used frequently in daily practice, but use of the other advanced technologies is not routine. High-definition white light endoscopy and random four quadrant biopsy remain the standard of care for evaluation of Barrett's esophagus; this is largely due to the value of advanced imaging technologies not having been validated in large studies or in everyday practice. A new advanced imaging technology called volumetric laser endomicroscopy is commercially available in the United States. Its ease of use and rapid acquisition of high-resolution images make this technology very promising for widespread application. In this article we review the technology and its potential for advanced imaging in Barrett's esophagus.


advanced imaging; cancer; dysplasia; esophagus

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center