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Urol Clin North Am. 2016 May;43(2):233-7. doi: 10.1016/j.ucl.2016.01.012. Epub 2016 Mar 21.

Testosterone Deficiency and Sleep Apnea.

Author information

1
Mount Sinai School of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, 11 East 26th Street, 13th Floor, New York, NY 10010, USA.
2
NYU School of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, 462 First Avenue Room 7N24, New York, NY 10016, USA. Electronic address: jing.wang@nyumc.org.

Abstract

Obstructive sleep apnea (OSA) is a common condition among middle-aged men and is often associated with reduced testosterone (T) levels. OSA can contribute to fatigue and sexual dysfunction in men. There is suggestion that T supplementation alters ventilatory responses, possibly through effects on central chemoreceptors. Traditionally, it has been recommended that T replacement therapy (TRT) be avoided in the presence of untreated severe sleep apnea. With OSA treatment, however, TRT may not only improve hypogonadism, but may also alleviate erectile/sexual dysfunction.

KEYWORDS:

Continuous positive airway pressure; Obstructive sleep apnea; Sexual dysfunction; Testosterone deficiency

PMID:
27132581
DOI:
10.1016/j.ucl.2016.01.012
[Indexed for MEDLINE]

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