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Hipertens Riesgo Vasc. 2016 Oct - Dec;33(4):133-144. doi: 10.1016/j.hipert.2016.03.001. Epub 2016 Apr 27.

[Medical expert consensus in AH on the clinical use of triple fixed-dose antihypertensive therapy in Spain].

[Article in Spanish]

Author information

1
Servicio de Cardiología, Hospital Clínico Universitario, Santiago de Compostela, España. Electronic address: pilarmazon@yahoo.es.
2
Servicio de Cardiología, Hospital Vall d'Hebrón, Barcelona, España.
3
Servicio de Medicina Interna, Hospital Infanta Sofía, Madrid, España.
4
Servicio de Nefrología, Hospital Universitario Central de Asturias, Oviedo, España.
5
Servicio de Nefrología, Hospital Universitario Dr. Peset, Valencia, España.
6
Unidad de Hipertensión, Hospital Virgen de las Nieves, Granada, España.

Abstract

INTRODUCTION:

The opinion of experts (different specialties) on the triple fixed-dose antihypertensive therapy in clinical practice may differ.

MATERIALS AND METHODS:

Online questionnaire with controversial aspects of the triple therapy answered by panel of experts in hypertension (HT) using two-round modified Delphi method.

RESULTS:

The questionnaire was completed by 158 experts: Internal Medicine (49), Nephrology (26), Cardiology (83). Consensus was reached (agreement) on 27/45 items (60%); 7 items showed differences statistically significant. Consensus was reached regarding: Predictive factors in the need for combination therapy and its efficacy vs. increasing the dose of a pretreatment, and advantage of triple therapy (prescription/adherence/cost/pressure control) vs. free combination.

CONCLUSIONS:

This consensus provides an overview of the clinical use of triple therapy in moderate-severe and resistant/difficult to control HT.

KEYWORDS:

Antihipertensivos; Antihypertensive drugs; Arterial hypertension; Combinación de medicamentos; Drug combination; Hipertensión arterial

PMID:
27129628
DOI:
10.1016/j.hipert.2016.03.001
[Indexed for MEDLINE]

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