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Clin Nucl Med. 2016 Aug;41(8):e390-1. doi: 10.1097/RLU.0000000000001233.

18F-Fluorocholine PET/CT Finding of a Vertebral Hemangioma.

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From the Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.


The uptake of F-fluorocholine (FCH), a radiopharmaceutical used to study patients with prostate cancer, follow both the phosphorylcholine and acetylcholine synthesis. FCH uptake is not specific of neoplastic cells because phospholipids are a structural constituent of the membrane of all cells. Thus, PET/CT with FCH show several areas of physiologic uptake. The skeleton concentrates only mild amounts of FCH, thus a diffuse faint uptake of the radiopharmaceutical is present at a PET/CT study. Herein we present the case of a patient in which PET/CT evidenced a sharply defined vertebral "cold" area of reduced FCH uptake corresponding to a vertebral hemangioma.

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