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Infect Genet Evol. 2016 Aug;42:49-52. doi: 10.1016/j.meegid.2016.04.026. Epub 2016 Apr 22.

Norovirus epidemics caused by new GII.2 chimera viruses in 2012-2014 in Japan.

Author information

1
Osaka University, Osaka 565-0871, Japan. Electronic address: kmotomura@biken.osaka-u.ac.jp.
2
Osaka University, Osaka 565-0871, Japan.
3
National Institute of Health Sciences, Tokyo 158-8501, Japan.
4
Sakai City Institute of Public Health, Osaka 590-0953, Japan; Hidaka General Hospital, Wakayama 644-0002, Japan.

Abstract

The new GII.2 variant collected from May 2012-March 2014 consisted of GII.15 and GII.2 genomes, in which the putative recombination points found in the boundary region between ORF1 and ORF2. These findings suggested that the swapping of structural and non-structural proteins is a common mechanism for generating new epidemic variants in nature.

KEYWORDS:

GII.2; New chimera virus; Norovirus

PMID:
27112386
DOI:
10.1016/j.meegid.2016.04.026
[Indexed for MEDLINE]

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