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Dev Cell. 2016 Apr 18;37(2):105-6. doi: 10.1016/j.devcel.2016.04.006.

Centromeres of a Different CAL-ibre.

Author information

1
Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
2
Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: dfoltz@northwestern.edu.

Abstract

Centromeres of higher eukaryotes are defined by the epigenetic inheritance of the centromere-specific CENP-A nucleosome. Reporting in Developmental Cell, Rosin and Mellone (2016) show that co-evolution of the CENP-A histone variant and its chaperone CAL1 accounts for species incompatibility between centromeric histones in Drosophila.

PMID:
27093076
DOI:
10.1016/j.devcel.2016.04.006
[Indexed for MEDLINE]
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