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J Pediatr Orthop B. 2017 Jan;26(1):48-52.

Vitamin-D measurement in patients with adolescent idiopathic scoliosis.

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Departments of aOrthopaedics and Traumatology bSports Medicine, M.H. Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Baltalimani, Istanbul, Turkey.


Our retrospective study compared vitamin-D levels in 229 patients with adolescent idiopathic scoliosis (AIS) and 389 age-matched controls, and evaluated the correlation between vitamin-D levels and sex, Cobb's angle, and serum levels of calcium (Ca), phosphorus, and alkaline phosphatase in the AIS group. Vitamin-D levels were lower in the AIS group, with no sex-specific effects, indicative of a possible vitamin-D resistance in AIS. Vitamin-D levels correlated positively with Ca levels and negatively with Cobb's angle, indicative of a possible role of vitamin D in the etiopathogenesis of AIS. Patients with AIS should be monitored for vitamin-D deficiency/insufficiency.

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