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Heart Fail Rev. 2016 May;21(3):299-308. doi: 10.1007/s10741-016-9551-x.

Pulmonary hypertension associated with lung diseases and hypoxemia.

Author information

1
Northwestern Pulmonary Hypertension Program, 676 St Claire Suite 1400, Chicago, IL, 60611, USA. m-cuttica@northwestern.edu.

Abstract

Pulmonary hypertension that develops in the setting of underlying lung diseases such as COPD or idiopathic pulmonary fibrosis (IPF) is associated with decreased functional status, worsening hypoxemia and quality of life, and increased mortality. This complication of lung disease is complex in its origin and carries a unique set of diagnostic and therapeutic issues. This review attempts to provide an overview of mechanisms associated with the onset of pulmonary hypertension in COPD and IPF, touches on appropriate evaluation, and reviews the state of knowledge on treating pulmonary hypertension related to underlying lung disease.

KEYWORDS:

COPD; Idiopathic pulmonary fibrosis; Pulmonary hypertension; Treatment

PMID:
27086030
DOI:
10.1007/s10741-016-9551-x
[Indexed for MEDLINE]

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