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Curr Opin Microbiol. 2016 Jun;31:154-160. doi: 10.1016/j.mib.2016.03.014. Epub 2016 Apr 14.

Flexible genomic islands as drivers of genome evolution.

Author information

1
Evolutionary Genomics Group, Departamento de Producción Vegetal y Microbiología, Universidad Miguel Hernández, San Juan de Alicante, 03550 Alicante, Spain. Electronic address: frvalera@umh.es.
2
Evolutionary Genomics Group, Departamento de Producción Vegetal y Microbiología, Universidad Miguel Hernández, San Juan de Alicante, 03550 Alicante, Spain.

Abstract

Natural prokaryotic populations are composed of multiple clonal lineages that are different in their core genomes in a range that varies typically between 95 and 100% nucleotide identity. Each clonal lineage also carries a complement of not shared flexible genes that can be very large. The compounded flexible genome provides polyclonal populations with enormous gene diversity that can be used to efficiently exploit resources. This has fundamental repercussions for interpreting individual bacterial genomes. They are better understood as parts rather than the whole. Multiple genomes are required to understand how the population interacts with its biotic and abiotic environment.

PMID:
27085300
DOI:
10.1016/j.mib.2016.03.014
[Indexed for MEDLINE]

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