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Dev Biol. 1989 May;133(1):309-11.

Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro.

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1
INSERUM U114, Coll├Ęge de France, Paris.

Abstract

Amoeboid microglial cells purified from primary cultures of embryonic rat brains and stimulated with bacterial lipopolysaccharides released high amounts of nerve growth factor. This finding suggests that brain macrophages play a major neurotrophic role during development, in adulthood, and in the regenerative events that follow localized lesions.

PMID:
2707484
[Indexed for MEDLINE]
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