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Rev Esp Salud Publica. 2016 Apr 13;90:E15.

[Cost Effectiveness of Treatments of Psoriasis with a PASI 75 and one Period of 12 Weeks].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Servicio de Dermatología. Hospital Universitario Puerta de Hierro. Madrid.feralfarol@yahoo.es.
2
Departamento de Economía Aplicada. Universidad Autónoma de Madrid. España.
3
Departamento de Análisis Económico I. Universidad Nacional de Educación a Distancia. España.
4
Departamento de Administración de Servicios de Enfermería. Universidad Nacional de Educación a Distancia. España.

Abstract

in English, Spanish

OBJECTIVE:

The objective was to evaluate the efficiency (relation between the cost and the results in health) of the treatments in psoriasis, seeking a higher quality of economic evaluations, consistency and transparency in these studies.

METHODS:

We developed a model of economic evaluation in psoriasis collecting all the many direct and indirect costs of each treatment. The effectiveness indicator used was Psoriasis Area Severity Index [PASI 75] which is generally acceptable in studies of psoriasis. The effectiveness indicator was a PASI 75.Subsequently we calculated the Incremental Cost-Effectiveness Ratio (ICER) for the period of 12 weeks and PASI 75, ordering treatments by level of effectiveness at the expense of treatment costs.

RESULTS:

The most cost effective treatment was methotrexate (ICER -7.5) followed by acitretin (ICER 29.5). The least cost has proved effective PUVA (ICER 4,651), followed by UVB narrow band (2,886.1).

CONCLUSIONS:

when taking into account both direct and indirect costs together with efficiency, methotrexate is the most cost effective treatment.

KEYWORDS:

Adalimumab; Cost-Effectiveness Analysis; Economic Evaluation; Infliximab; Methotrexate; Psoriasis; Spain; Ustekinumab

PMID:
27073006
[Indexed for MEDLINE]
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