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Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids.
FEBS Lett. 2016 May;590(9):1304-12. doi: 10.1002/1873-3468.12167. Epub 2016 Apr 17.
FEBS Lett. 2016.
PMID: 27059013
Free PMC article.
Human mitochondrial cytochrome P450 27C1 is localized in skin and preferentially desaturates trans-retinol to 3,4-dehydroretinol.
Johnson KM, Phan TTN, Albertolle ME, Guengerich FP.
Johnson KM, et al.
J Biol Chem. 2017 Aug 18;292(33):13672-13687. doi: 10.1074/jbc.M116.773937. Epub 2017 Jul 12.
J Biol Chem. 2017.
PMID: 28701464
Free PMC article.
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