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Breastfeed Med. 2016 Jun;11:261-3. doi: 10.1089/bfm.2016.0025. Epub 2016 Apr 8.

Treatment of Narcolepsy with Sodium Oxybate While Breastfeeding: A Case Report.

Author information

1
1 Department of Pharmacy, University of Rochester Medical Center , Rochester, New York.
2
2 Department of Pediatrics School of Medicine and Dentistry, University of Rochester Medical Center , Rochester, New York.

Abstract

BACKGROUND:

Sodium oxybate is used in the treatment of narcolepsy. Currently no published literature supports its safety during breastfeeding, although it has a favorable pharmacokinetic profile for minimizing exposure.

MATERIALS AND METHODS:

We report a case of a 27-year-old primigravida with narcolepsy who was taking sodium oxybate for symptom control and contacted our Lactation Study Center for advice. Based on our current pharmacokinetic knowledge, she was advised to avoid breastfeeding 4 hours after a dose.

RESULTS:

Follow-up phone interviews were done and the patient reported that the feeding schedule was manageable, and she was able to exclusively breastfeed for 6 months of her infant's life. Based on pediatric records, her infant's growth and development were excellent. There were no noted side effects of the medication for the infant.

CONCLUSIONS:

This is the first report to our knowledge of breastfeeding during maternal therapy with sodium oxybate, which appears to be compatible with safe, exclusive breastfeeding when managed appropriately.

PMID:
27057786
PMCID:
PMC4921898
DOI:
10.1089/bfm.2016.0025
[Indexed for MEDLINE]
Free PMC Article

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