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Vet World. 2015 Jan;8(1):66-71. doi: 10.14202/vetworld.2015.66-71. Epub 2015 Jan 21.

Evaluation of pesticide residues in human blood samples from Punjab (India).

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1
Department of Veterinary Public Health and Epidemiology, School of Public Health and Zoonoses, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.

Abstract

AIM:

The present study was undertaken to estimate the current status of residues of organochlorine pesticides (OCPs), organophosphates (OPs) and synthetic pyrethroids (SPs) pesticides in human blood.

MATERIALS AND METHODS:

Human blood samples were analyzed by gas chromatography and confirmed by gas chromatography-mass spectrometry in selective ion monitoring mode.

RESULTS:

The gas chromatographic analysis of human blood samples collected from Punjab revealed the presence of p,p'-dichlorodiphenyl dichloroethylene (DDE), p,p' dichlorodiphenyl dichloroethane (DDD), o,p' DDE and β-endosulfan at mean levels of 15.26, 2.71, 5.62 and 4.02 ng/ml, respectively. p,p' DDE residue was observed in 18.0% blood samples, and it contributes 55% of the total pesticide burden in human blood. The difference of total dichlorordiphenyl trichloroethane (DDT) between different age groups of humans was found to be statistically significant (p<0.05). The difference of DDT and endosulfan between dietary habits, gender and spraying of pesticides was found statistically non-significant, however endosulfan residues were observed only in pesticide sprayer's population.

CONCLUSION:

Occurrence of p,p' DDE, p,p' DDD, o,p' DDE in human blood indicated restricted use of DDT. However, presence of endosulfan residues in occupationally exposed population is a matter of public health concern.

KEYWORDS:

Punjab; dichlorordiphenyl trichloroethan; endosulfan; human blood; residues

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