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Clin Microbiol Rev. 2016 Jul;29(3):429-47. doi: 10.1128/CMR.00090-15.

The Point-of-Care Laboratory in Clinical Microbiology.

Author information

1
Aix Marseille Université, URMITE, UMR CNRS 7278, IRD 198, INSERM 1095, IHU Méditerranée Infection, Marseille, France michel.drancourt@univ-amu.fr.
2
Aix Marseille Université, URMITE, UMR CNRS 7278, IRD 198, INSERM 1095, IHU Méditerranée Infection, Marseille, France Aix Marseille Université, Aix Marseille School of Economics-SESSTIM UMR 912, INSERM IRD, Marseille, France.
3
Aix Marseille Université, Aix Marseille School of Economics-SESSTIM UMR 912, INSERM IRD, Marseille, France.
4
Aix Marseille Université, URMITE, UMR CNRS 7278, IRD 198, INSERM 1095, IHU Méditerranée Infection, Marseille, France.

Abstract

Point-of-care (POC) laboratories that deliver rapid diagnoses of infectious diseases were invented to balance the centralization of core laboratories. POC laboratories operate 24 h a day and 7 days a week to provide diagnoses within 2 h, largely based on immunochromatography and real-time PCR tests. In our experience, these tests are conveniently combined into syndrome-based kits that facilitate sampling, including self-sampling and test operations, as POC laboratories can be operated by trained operators who are not necessarily biologists. POC laboratories are a way of easily providing clinical microbiology testing for populations distant from laboratories in developing and developed countries and on ships. Modern Internet connections enable support from core laboratories. The cost-effectiveness of POC laboratories has been established for the rapid diagnosis of tuberculosis and sexually transmitted infections in both developed and developing countries.

PMID:
27029593
PMCID:
PMC4861988
DOI:
10.1128/CMR.00090-15
[Indexed for MEDLINE]
Free PMC Article

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