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Zhonghua Wai Ke Za Zhi. 2016 Apr 1;54(4):317-20. doi: 10.3760/cma.j.issn.0529-5815.2016.04.018.

[The application progress of human urine derived stem cells in bone tissue engineering].

[Article in Chinese]

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Department of Pediatric Surgery, Harbin Children's Hospital, Harbin 150010, China.


The research of bone tissue engineering bases on three basic directions of seed cells, scaffold materials and growth information. Stem cells have been widely studied as seed cells. Human urine-derived stem cell (hUSC) is extracted from urine and described to be adhesion growth, cloning, expression of the majority of mesenchymal stem cell markers and peripheral cell markers, multi-potential and no tumor but stable karyotype with passaging many times. Some researches proposed that hUSC might be a new source of seed cells in tissue engineering because of their invasive and convenient obtention, stable culture and multiple differentiation potential.

[Indexed for MEDLINE]

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