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Turk J Gastroenterol. 2016 Mar;27(2):91-6. doi: 10.5152/tjg.2015.150186.

Reasonable decision of anesthesia methods in patients who underwent endoscopic submucosal dissection for superficial esophageal carcinoma: A retrospective analysis in a single Japanese institution.

Author information

1
Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. takujigotoda@yahoo.co.jp.

Abstract

BACKGROUND/AIMS:

Despite being a valuable therapeutic option, it has not yet been reported whether endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma should be performed under general or non-general anesthesia (sedation).

MATERIALS AND METHODS:

The clinicopathological factors (age, sex, histology, tumor size, tumor location, tumor macroscopic morphology, and adverse events) of 110 superficial esophageal carcinoma lesions (98 patients) treated by ESD at a single Japanese institution from January 2007 to December 2013 were retrospectively reviewed using medical records.

RESULTS:

Among 110 lesions, 94 lesions were resected under general anesthesia, and 16 lesions were resected under non-general anesthesia by an experienced endoscopist. Although the number of complications was 12 in the group of general anesthesia and 1 in sedated patients, no significant differences between both groups were found in the incidence of adverse events (total adverse events: 12.2% versus 1.02%, p=0.456; mediastinal emphysema: 11.2% versus 1.02%, p=0.518; pulmonary atelectasis: 1.02% versus 0%, p=0.679). All of the events could be managed conservatively.

CONCLUSION:

For ordered management of accidental events during esophageal ESD, general anesthesia might be a crucial option for a better clinical outcome even when administered by non-experienced operators.

PMID:
27015614
DOI:
10.5152/tjg.2015.150186
[Indexed for MEDLINE]
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