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J Int Soc Prev Community Dent. 2016 Jan-Feb;6(1):1-6. doi: 10.4103/2231-0762.175416.

Dengue virus: A global human threat: Review of literature.

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Department of Oral Medicine and Radiology, Jamia Millia Islamia, New Delhi, India.
Department of Oral and Maxillofacial Surgery, Teerthankar Mahaveer Dental College, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Buraydah College of Dentistry and Pharmacy, Al Qassim, Saudi Arabia.
Department of Conservative Dentistry and Endodontics, Specialist Dental Center, Hafer Al Batin, Saudia Arabia.


Dengue is an acute viral illness caused by RNA virus of the family Flaviviridae and spread by Aedes mosquitoes. Presenting features may range from asymptomatic fever to dreaded complications such as hemorrhagic fever and shock. A cute-onset high fever, muscle and joint pain, myalgia, cutaneous rash, hemorrhagic episodes, and circulatory shock are the commonly seen symptoms. Oral manifestations are rare in dengue infection; however, some cases may have oral features as the only presenting manifestation. Early and accurate diagnosis is critical to reduce mortality. Although dengue virus infections are usually self-limiting, dengue infection has come up as a public health challenge in the tropical and subtropical nations. This article provide a detailed overview on dengue virus infections, varied clinical manifestations, diagnosis, differential diagnosis, and prevention and treatment.


Breakbone fever; cutaneous rash; dengue virus; dental and public health; hemorrhagic diathesis; oral manifestations

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